Comment to 'why do dobermans seem weak?!?!?!'
  • The bottom line for the Doberman.......

    The Doberman has the lowest diversity in the DLA genes of the immune system of any breeds studied to date by Pedersen's lab at UC Davis. This, together with the high level of inbreeding documented from multiple studes and the overall relatedness of the dogs in the population, leaves breeders with little ability to circumvent the multiple genetic diseases in the breed. Furthermore, some deleterious genes could be fixed in the breed - that is, the normal, non-mutated version of the gene is no longer present in the gene pool and therefore are not available for selection.

    It is highly unlikely that the desperate genetic situation of the Doberman can be improved by selective breeding within the closed gene pool of the breed. Breeders cannot restore health to this breed by selecting against health problems. Furthermore, trying to select less related parents in an effort to improve diversity in the offspring is a bit like pushing your peas around on your plate; you might look like you're accomplishing something, but with little effect.The only hope for this breed is the initiation of a sound, comprehensive cross-breeding program, under the guidance of population geneticists, that will introduce new genetic diversity into the breed. The longer it takes to begin genetic rescue, the more difficult it will be and the less likely it is to be successful.