Log in

Not a member yet? Sign up.
Wendy
 added a post 

These dogs are in the mountain of China. Dont look healthy but at least outside and not in cage.

 

Elite Guardian Presa has produced some outstanding working dogs. This breeding has Show prospects as well as great working dogs. They are truly Performance Presa Canario. 

eliteguardianpresa.com

 

  • Your dogs are awesome looking so I am sure your breedings are top notch. Great looking kennel. :)

    0 0 0 0 0 0
    • These dogs are kept indoors. We have runs similar inside. They go outside for exercise and to potty. We are keeping the brindle male up front. We are likely to keep one of the females. Initially it was going to be the red fawn. But as they continued to develop we don’t want to let any of them go. It will be easier to part with the brindle female because we have several brindle females. We shall see....smh

      0 0 0 0 0 0
    • Thanks!! It is our goal in reproduction to maintain the breed standards both conformation and temperament. We expect our dogs to be able to what they were bred to do. These are working dogs. We expect them to perform. While there is little need to be a catch dog there’s a need to protect the family and property. 

      0 0 0 0 0 0
      Not logged in users can't 'Comments Post'.
      Polina
       added an album 
      • Another beautiful pup from Polina

        0 0 0 0 0 0
        • Nice

          0 0 0 0 0 0
          Not logged in users can't 'Comments Post'.
          HerNibs
           added a post 

          Paper in review on ancient e allele found across a number of current breeds and landraces, and found present in the DNA samples of over 10,000 year old prehistoric Siberian and South-Eastern European dogs:

          https://www.researchsquare.com/article/rs-36023/v1

          • Coat color genetics is a very intriguing topic. I have rudimentary understanding of it but I always defer to the experts. That article is very informative and prompted me to continue my research on the subject - my poor brain.

            0 0 0 0 0 0
            • It's something I'm involved with for a living, and we learn something nearly every week! If it helps you feel better, human geneticists I've talked to say that we know more (and therefore there's more complexity) about it in dogs than in humans :-)

              0 0 0 0 0 0
              Not logged in users can't 'Comments Post'.
              Gary
               added a post 

              The messenger server was restarted and the Shout Box is not working fine.  Give it a try.

              • Hello Hello MD land!!!!

                0 0 0 0 0 0
                • Yeahhhh... works now.. Mastini Land

                  0 0 0 0 0 0
                  Not logged in users can't 'Comments Post'.

                  Date: May 29, 2020

                  Source: University of Helsinki

                  Summary: Researchers have identified a new genomic region and anxiety-related candidate genes associated with fearfulness in dogs. Findings support their hypothesis that fearfulness and anxiety are hereditary traits in dogs, and there may be shared factors underlying anxiety in both humans and dogs.

                  The identified genomic region includes several candidate genes associated with brain development and function as well as anxiety, whose further analysis may reveal new neural mechanisms related to fear.

                  For the purposes of the study, carried out by Professor Hannes Lohi's research group and published in the Translational Psychiatry journal, data from a total of 120 Great Danes was collected. The Great Dane breed is among the largest dog breeds in the world.

                  The project was launched after a number of Great Dane owners approached the research group to tell them about their dogs' disturbing fearfulness towards unfamiliar human beings in particular.

                  "Fear in itself produces a natural and vital reaction, but excessive fear can be disturbing and results in behavioural disorders. Especially in the case of large dogs, strongly expressed fearfulness is often problematic, as it makes it more difficult to handle and control the dog," says Riika Sarviaho, PhD from the University of Helsinki.

                  In dogs, behavioural disorders associated with anxiety and fearfulness include generalised anxiety disorder and a range of phobias. Fear can be evidenced, for example, as the dog's attempt to flee from situations they experience as frightening. At its worst, fear can manifest as aggression, which may result in attacks against other dogs or humans.

                  "Previous studies have suggested that canine anxiety and fearfulness could correspond with anxiety disorder in humans. In fact, investigating fearfulness in dogs may also shed more light on human anxiety disorders and help [us] understand their genetic background," Professor Lohi explains the broader goal of the study.

                  A new genomic region underlying fearfulness

                  The study utilised a citizen science approach as the dog owners contributed by completing a behavioural survey concerning their dogs, in which the dogs received scores according to the intensity of fear. Through genetic research, a genomic region associated with fearfulness was identified in chromosome 11. The analysis was repeated by taking into consideration the socialisation carried out in puppyhood, or the familiarisation of the dogs with new people, dogs and situations. The re-analysis reinforced the original finding.

                  "In the case of behavioural studies, it's important to keep in mind that, in addition to genes, the environment has a significant impact on the occurrence of specific traits. For dogs, the socialisation of puppies has been found to be an important environmental factor that strongly impacts fearfulness. In this study, the aim was to exclude the effect of puppyhood socialisation and, thus, observe solely the genetic predisposition to fearfulness," says Sarviaho.

                  The genomic region was studied in more detail also with the help of whole genome sequencing, but, so far, the researchers have not succeeded in identifying in it a specific gene variant that predisposes to fearfulness.

                  "Although no actual risk variant was identified, the genomic region itself is interesting, as it contains a number of genes previously associated in various study models with neural development and function, as well as anxiety. For example, the MAPK9 gene has been linked with brain development and synaptic plasticity as well as anxiety, while RACK1 has been associated with neural development and N4BP3 with neurological diseases," says Professor Lohi.

                  Link between accelerated puppyhood growth and timidity?

                  A genomic region in humans corresponding with the one now associated with canine fearfulness is linked to a rare syndrome, which causes both neurological symptoms and, among other things, accelerated growth in childhood.

                  "Research on the topic is only at the early stages and findings have to be carefully interpreted, but it's interesting to note, when focusing on a particularly large dog breed, that the genomic region associated with fearfulness appears to have a neurological role as well as one related to growth," Sarviaho adds.

                  So far, gene discoveries in canine behavioural research have remained fairly rare, and the genomic region now identified has not previously been linked with fearfulness. Lohi's research group has previously described two genomic regions associated with canine generalised fear and sensitivity to sound. The genetic research findings support the hypothesis that fearfulness and anxiety are inherited traits. To be able to identify more detailed risk factors and confirm the relevance of the findings, the study should be repeated with a more extensive dataset.

                   

                  Story Source:

                  Materials provided by University of Helsinki. Original written by Hannes Lohi, Comms Viikki. Note: Content may be edited for style and length.


                  Journal Reference:

                  1. R. Sarviaho, O. Hakosalo, K. Tiira, S. Sulkama, J. E. Niskanen, M. K. Hytönen, M. J. Sillanpää, H. Lohi. A novel genomic region on chromosome 11 associated with fearfulness in dogs. Translational Psychiatry, 2020; 10 (1) DOI: 10.1038/s41398-020-0849-z

                  Cite This Page:

                  University of Helsinki. "Fearful Great Danes provide new insights to genetic causes of fear." ScienceDaily. ScienceDaily, 29 May 2020. <www.sciencedaily.com/releases/2020/05/200529150627.htm>.
                  Latest Articles (Gallery View)
                  Shoutbox
                  Admin
                  Testing the shoutbox
                  Admin
                  Hello world.
                  gsicard
                  Hello chat box
                  gsicard
                  Jess.. write something here.
                  Gary_Sicard
                  What a great day in south Texas. We have rain and cool temperature.. Awesome
                  Gary_Sicard
                  Posting from a mobile phone. Let's see if it works.
                  mastini-mayhem
                  Hello! Also posting off my cell :-) working good.
                  Gary_Sicard
                  Awesome Jess. Thanks.
                  Gary Admin
                  I just rearranged the site homepage so let mebknow if you like it.
                  Tim Burleigh
                  Hey Gary!
                  Gary_Sicard
                  Hola Timmy.. Hope you are well my friend. The Crawfish Boil and Danny Brewer party is cancelled because of Corona Virus. 😂
                  Tim Burleigh
                  Yep, maybe at a later date?
                  gsicard
                  Certainly. Will let you know
                  Tim Burleigh
                  10-4
                  mastini-mayhem
                  Hey all!~Hope everyone has a wonderful Monday!
                  Admin
                  Message was removed.
                  Admin
                  Message was removed.
                  Gary
                  TMD had to reboot the jot server and the messenger is working again.. yeahhh
                  Gary
                  Message was removed.
                  typing a message...
                  Connecting
                  Connection failed
                  Discussions With Recent Posts
                  1-12