Your welcome The contents of Advocate for dogs over 25 kilos is 100g/L IMIDACLOPRID 25g/L MOXIDECTIN With pups you are supposed to treat the mother for the 2 to 4 treatments and just before breeding and 4 week intervals preferably not just after whelp and you can buy the one for pups but not sure at what age you can start. Will ask my vet when I next go into town.