I've formed the opinion from my research that inbreeding should only be done occasionally, and you should be prepared to accept the consequences (surprises) that arise. Line breeding I'm a little more comfortable with, but not too closely in our breed right now. And to many people outcross with no clue why they're doing it. In regards to the human inbreeding Deb..I actually did see an article in a magazine..I think it was popular science or maybe Time. It was about human inbreeding/linebreeding, specifically the rule about 1st cousins. Technically, they said, they're nothing scientifically wrong with it.